A brand new research printed within the peer-reviewed OMICS: A Journal of Integrative Biology recognized genes for virulence and antimicrobial resistance in two micro organism that co-occur with C. difficile, suggesting these pathogens as rising potential threats in planetary well being.
Thokur Sreepathy Murali, PhD, Ankit Singh Tanwar, Padival Shruptha and colleagues from Manipal Academy of Greater Training, India, and co-author Angela Model, MD, PhD, MPH from Maastricht College, The Netherlands, carried out comparative genome analyses of three Clostridia species, C. difficile, C. butyricum, and C. tertium.
C. difficile could cause diarrhea, colitis, sepsis and a number of organ dysfunction. C. butyricum and C. tertium, which reside within the intestine, can harbor toxin/virulence genes, and thus, might pose a menace to human well being.
Research resembling this one “will additional enhance our understanding of growth of antimicrobial resistance, present new avenues in genomic monitoring of rising pathogens and supply higher therapy methods for crippling infectious illnesses,” state the investigators.
The research offers a well timed utility of comparative genomics in planetary well being and opens up new avenues for diagnostics and therapeutics innovation. The findings unpack the potential threats and interactions of three Clostridia species. I welcome new manuscripts on multi-omics functions in planetary well being for peer-review within the journal.”
Vural Özdemir, MD, PhD, DABCP, Editor-in-Chief of OMICS
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Journal reference:
Tanwar, A. S., et al. (2023) Rising Pathogens in Planetary Well being and Classes from Comparative Genome Analyses of Three Clostridia Species. OMICS A Journal of Integrative Biology. doi.org/10.1089/omi.2023.0034.
