Homocysteine is an amino acid that is closely concerned in a organic course of known as methylation. Throughout methylation, the bioactive type of folate (5-MTHF) donates a methyl group to homocysteine so it may be transformed into one other amino acid, methionine. When working optimally, methylation promotes cardiovascular, neurological, and reproductive well being; aids vitality manufacturing; bolsters detoxing pathways; helps longevity; and extra.
The issue is that greater than 50% of the U.S. inhabitants has a genetic mutation of the MTHFR gene that inhibits the physique’s potential to activate folate, so it cannot optimize methylation. If bioactive folate is not out there to assist convert homocysteine in the course of the methylation cycle (i.e., attributable to an MTHFR gene variation or different causes—corresponding to poor weight loss program, hormone imbalances, stress, or publicity to toxins), homocysteine ranges can change into too excessive.
Elevated homocysteine ranges are linked to the next threat of continual irritation, poor detoxing, heart problems, autoimmune circumstances, and sure—dementia.
